Edgard Colle (18 May 1897, in Ghent, Belgium – 19 April 1932) was a Belgian chess master.
He scored excellent results in major international tournaments, including first at Amsterdam 1926, ahead of Savielly Tartakower and future world champion Max Euwe; first at Meran 1926, in a strong field ahead of Esteban Canal; and won twice outright at Scarborough in 1927, and again in 1930, ahead of Maróczy and Rubinstein.
Colle's playing career was hampered by ill health.
He survived three difficult operations for a gastric ulcer and died after a fourth at the age of 34 in Ghent.