Mário de Castro (30 June 1905 – 29 April 1998) was a Brazilian footballer who played as forward.
He spent his entire career at Atlético Mineiro, with whom he won three Campeonato Mineiro titles, a competition of which he was top goalscorer twice.
Mário was the first Atlético Mineiro player to be called up for the Brazilian national football team, and scored 195 goals in 100 matches for the club.