Johann Jakob Wepfer, Date of Birth, Place of Birth, Date of Death

    

Johann Jakob Wepfer

Swiss pathologist

Date of Birth: 23-Dec-1620

Place of Birth: Schaffhausen, Switzerland

Date of Death: 26-Jan-1695

Profession: pharmacologist, pathologist

Nationality: Switzerland

Zodiac Sign: Capricorn


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About Johann Jakob Wepfer

  • Johann Jakob Wepfer (December 23, 1620 – January 26, 1695) was a Swiss pathologist and pharmacologist who was a native of Schaffhausen. He studied medicine in Strasbourg, Basel and Padua, and in 1647 returned to Schaffhausen to practice medicine.
  • Here he maintained a practice that extended into southern Germany.
  • During his career he also served as a private physician and consultant to various members of royalty. Wepfer is remembered for his work involving vascular anatomy of the brain, and the study of cerebrovascular disease.
  • He was the first physician to hypothesize that the effects of a stroke were caused by bleeding in the brain.
  • He also mentioned that these symptoms could be caused by a blockage of one of the main arteries that supply blood to the brain.
  • From postmortem studies, he provided information on the carotid and vertebral arteries that supply the brain with blood.
  • in 1658 he published a classic treatise on strokes, titled Historiae apoplecticorum. Wepfer made important contributions in the fields of experimental pharmacology and toxicology.
  • He conducted experiments on the toxicity of water hemlock, hellebore, monkshood, and warned against the usage of arsenic, antimony, and mercury in medicine.
  • In the fields of pharmacology/toxicology he published an influential work on water and poison hemlock called Cicutae aquaticae historia et noxae (1679).
  • This contained the first reports of toxicity of plants from the genus Cicuta, ultimately attributed to compounds such as cicutoxin and oenanthotoxin.
  • Since 2005 an annual award for stroke research, named after Wepfer, is awarded at the European stroke conference.,

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