David Brydie Mitchell (October 22, 1766 – April 22, 1837) was an American politician in Georgia who was elected in 1809 as governor of the state, serving two terms.
He was elected again in 1815 for one term.
Mitchell moved to Georgia at the age of 24.
He had earlier been elected as mayor of Savannah and was appointed as state attorney general.
He also served three terms in the Georgia legislature, two in the General Assembly, and one in the Senate.
Mitchell resigned from the governorship in 1817 to accept an appointment by President James Monroe as United States Indian Agent to the Creek Nation in their lands in present-day Georgia and Alabama.
He followed the more than two-decade tenure of Benjamin Hawkins.
In 1820 he was prosecuted for being involved in smuggling of American slaves from Spanish Florida.
He was replaced in 1821 by President Monroe, who appointed John Crowell.