Ivaylo Georgiev Kalfin (Bulgarian: ?????? ???????? ??????, born 30 May 1964) is a Bulgarian politician.
A three-term deputy, he was Minister of Foreign Affairs of Bulgaria and Deputy Prime Minister from 2005 to 2009 in the Stanishev Cabinet.
Kalfin was a Member of European Parliament between 2009 and 2014.
Between November 7, 2014 and May 2016 he served as Deputy Prime-Minister of Bulgaria, and Minister of Labor and Social Policy in the Second Borisov Cabinet.