Lorenzo Natali Pierucci Bondicchi (born 2 October 1922 in Florence, died 29 August 1989 in Rome) was an Italian politician for Christian Democracy, and a European Commissioner from 1977 to 1989.
He served as Vice-President of the European Commission and Commissioner for Enlargement, Environment and Nuclear Safety in the Jenkins Commission from 1977 to 1981.
He then served as Vice-President and Commissioner for Mediterranean Policy, Enlargement and Information in the Thorn Commission from 1981 to 1985.
He was Vice-President and held the portfolio of Cooperation, Development Affairs and Enlargement in the Delors Commission from 1985 to 1989.
He was a government minister in Italy from 1966 to 1972 and served as Minister of Agriculture from 1970.The Lorenzo Natali Prize is named in his honour.