Thomas Isaac (born 1952) is an Indian politician and economist who is serving as the Minister of Finance of the Indian state of Kerala and a central committee member of the Communist Party of India (Marxist).
He represents Alappuzha constituency in the Kerala State Legislative Assembly.
During his tenure as a member of the Kerala State Planning Board, he was in charge of the Peoples Planning in Kerala.
He also served as the Finance Minister of Kerala from 2006 to 2011.