Jean-François Séguier (French pronunciation: ?[??~ f??~swa segje]; 25 November 1703 – 1 September 1784) was a French archaeologist, epigraphist, astronomer and botanist from Nîmes.
He studied law in Montpellier, during which time, he developed a passion for botany.
He was a friend and collaborator to Scipio Maffei, with whom he took an extended scientific tour throughout Europe (1732–36).
In 1755 he became a member of the Académie de Nîmes, serving as its secrétaire perpétuel from 1765 to 1784.
In 1772 he became a member of the Académie royale des Inscriptions et Belles-Lettres.The plant genus Seguieria (family Petiveriaceae) commemorates his name, as do the botanical species Ranunculus seguieri (Vill., 1779) and Euphorbia seguieriana (Neck., 1770).