Santiago Pérez Fernández (born 5 August 1977 in Vega de Peridiello, Asturias) is a Spanish professional road bicycle racer, who last rode for Barbot–Efapel.
In March 2005, it was announced that he would be suspended for 2 years after having failed a test for homologous blood transfusion during the 2004 Vuelta a España.