She was already the widow of the banker Hippolyte Jouberthon (having born him one child, Anna, in 1799), and thus known as "Madame Jouberthon", when she became the second wife of Prince Lucien Bonaparte, a younger brother of Napoleon I of France.
She and her second husband had nine children, including:
Prince Charles Lucien Bonaparte (1803–1857)
Prince Paul Marie Bonaparte (1809–1827)
Prince Louis Lucien Bonaparte (1813–1891).
Prince Pierre Napoleon Bonaparte (1815–1881).