Isaiah "Ike" Charlton (born October 6, 1977) is a former professional Canadian football linebacker and currently the defensive backs coach for the Ottawa Redblacks of the Canadian Football League (CFL).
As a player, he most recently played for the Montreal Alouettes of the CFL.
He was drafted by the Seattle Seahawks in the second round (52nd overall) of the 2000 NFL Draft.
He played college football at Virginia Tech.
Charlton has also been a member of the Jacksonville Jaguars, New York Giants, Oakland Raiders, New England Patriots, Detroit Lions, and Winnipeg Blue Bombers.