Hamilton Hume (19 June 1797 – 19 April 1873) was an early explorer of the present-day Australian states of New South Wales and Victoria.
In 1824, along with William Hovell, Hume participated in an expedition that first took an overland route from Sydney to Port Phillip (near the site of present-day Melbourne).
Along with Sturt in 1828, he was part of an expedition of the first Europeans to find the Darling River.