She was the daughter of Johann Herman Krefting Buch (1776-1838) and Johanne Frideriche Falster (1781-1828).
In 1841, she was married to Marcus Thrane.
They settled in Lillehammer where she had been working as a governess.
From 1841 to 1846 they were running a private school for boys and girls.
From 1854, she worked for the periodical Arbeider-Foreningernes Blad, which her husband had started in 1849.Her husband was the leader of the first Norwegian labor movement.
During the time when her husband was imprisoned as a labor agitator (1855-1858), she worked hard to get him pardoned.
She was also editor of Arbeider-Foreningernes Blad during this period.
She suffered from both cholera and tuberculosis and died in Christiania (now Oslo) in 1862 at the age of 42.