After graduation, he became a reporter in Tientsin and Shanghai.
In 1942, Wei began working for the Ministry of Information, the predecessor organization to what became known as the Government Information Office.
He moved to Taiwan in 1949, and established the China News on 5 June 1949.
The publication was later renamed Taiwan News.
Alongside his role as the newspaper's founding publisher, Wei was also a Reuters correspondent and deputy director of the Central News Agency.
Wei became the managing director of the Broadcasting Corporation of China in 1954, leaving the position to succeed James Shen as head of the Government Information Office in 1966.
He accepted a promotion at the Central News Agency in 1972, serving as director until retirement in 1978.
Wei remained an adviser to Chiang Ching-kuo until he died of a heart attack on 7 October 1982, at Taipei Veterans General Hospital.