Yayoi Kitazume (?? ???, Kitazume Yayoi, born 26 March 1945) is a Japanese composer.
She is the daughter of the clarinettist and music pedagogue Risei Kitazume (1919–2004), who was president of the Japan Clarinet Society from 1980 to 1986, and the older sister of the composer Michio Kitazume.