Suresh H. Moolgavkar, Date of Birth, Place of Birth

    

Suresh H. Moolgavkar

Indian epidemiologist and mathematician

Date of Birth: 03-Jan-1943

Place of Birth: Mumbai, Maharashtra, India

Profession: mathematician, epidemiologist

Nationality: India

Zodiac Sign: Capricorn


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About Suresh H. Moolgavkar

  • Suresh H.
  • Moolgavkar M.D., Ph.D.
  • (born 3 January 1943 in Bombay, India) is a mathematician and epidemiologist at the University of Washington and the Fred Hutchinson Cancer Research Center in Seattle.
  • Among his many scientific contributions is the development of the two-stage clonal expansion (TSCE) model of carcinogenesis, also known as the Moolgavkar-Venzon-Knudson (MVK) model, a stochastic cell-level description of carcinogenesis based on Alfred G.
  • Knudson’s two-hit hypothesis.
  • In its original development the TSCE model represents tumor initiation as the first hit, followed by cell proliferation (clonal expansion) and malignant transformation as the second hit.
  • It has been interpreted as describing the initiation-promotion-progression sequence observed in chemical carcinogenesis and has been applied widely for the analysis of both experimental and epidemiological data for purposes of quantitative risk assessment.

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