Huda Yahya Zoghbi (Arabic: ??? ?????? ?????? Huda al-Hibri az-Zughbi; born 1954), born Huda El-Hibri, is a Lebanese-born American geneticist, and a professor at the Department of Molecular and Human Genetics, Baylor College of Medicine.
Her work helped elucidate mechanisms of Rett syndrome and spinocerebellar ataxia type 1.
In 2017, she was awarded the Canada Gairdner International Award and the Breakthrough Prize in Life Sciences.