Kham Ouane Boupha (born 5 December 1932 in Luang Prabang) is a Laotian soldier and politician.
Appointed to command Phongsali Province in the Kingdom of Laos in 1957 or 1958 while he was in his mid-twenties, he would maintain that base throughout the impending Laotian Civil War.
During that war, in April 1963, he would defect from government service to head the pro-communist Patriotic Neutralists movement.
At the end of the war, as the Communists succeeded to power through the Provisional Government of National Union, Kham Ouane Boupha was appointed Deputy Minister of Defense on 9 April 1974.
He was promoted to become Minister of Defense on 12 May 1975 and served as such for many years, even while he was also Minister of Justice.
He retired from cabinet rank in 2006, becoming a Minister in the Office of the Prime Minister.