Edward Swift Isham (January 15, 1836 – February 16, 1902) was an American lawyer and politician from Vermont.
The son of a justice of the Vermont Supreme Court, Isham attended Williams College and the Harvard School of Law before he was admitted to the bar in 1858.
He headed west, establishing a practice in Chicago, Illinois, in 1859.
The practice eventually became Isham Lincoln & Beale.
Isham also served one term in the Illinois House of Representatives.