John Wu Shi-zhen (January 19, 1921 – August 25, 2014) was a Roman Catholic archbishop.
Born in China, Wu Shi-zhen was ordained a priest in 1949.
In September 6, 1987, he was clandestinely consecrated as bishop, and from 1990 to 2011 was an archbishop ordinary of the Roman Catholic Archdiocese of Nanchang.