Sophie Charlotte of Württemberg (22 February 1671 – 11 September 1717), was a German noblewoman member of the House of Württemberg and by marriage Duchess of Saxe-Eisenach.
Born in Stuttgart, she was the ninth of eleven children of Eberhard III, Duke of Württemberg and his second wife, Countess Marie Dorothea Sophie of Oettingen-Oettingen.
From Sophie Charlotte's ten full-siblings, only she and his three (unmarried) brothers George Frederick, Louis and John Frederick survive adulthood; in addition, they had fourteen older half-siblings from their father's first marriage with Anna Katharina, Wild- and Rheingräfin of Salm-Kyrburg, of whom only eight survived: Sophie Louise (by marriage Margravine of Brandenburg-Bayreuth), Christine Fredericka (by marriage Duchess of Oettingen-Oettingen), Christine Charlotte (by marriage Princess of East Frisia), William Louis, Duke of Württemberg, Anna Katharine (unmarried), Eberhardine Katharine (by marriage Duchess of Oettingen-Oettingen), Frederick Charles, Duke of Württemberg-Winnental and Karl Maximilian (unmarried).