His uncles included Constantin Sion, author of a semi-fictitious noble genealogy (Arhondologia Moldovei); and spatar Antohi Sion, the rumored author of Izvodul lui Clanau, an outright forgery.
After spending two years (1837-1839) at Saint Sava College in Bucharest, the capital of Wallachia, he returned to his native Moldavia.
Entering the Ia?i-based provincial administration, he became a copyist at the Justice Department in 1842, followed by work as a clerk at the Interior Department.
He became a wanted man for his participation in the 1848 revolution, and so fled to Austrian-ruled Transylvania.
He returned to Ia?i in 1849, working as bureau chief at the Department of Church Property and Public Education.
From 1855, he worked at the State Archives.Subsequently, around the time of the Union of the Principalities, Sion moved to Bucharest, where his posts included membership in the Appeals Court and, from 1866, head of the Tobacco Monopoly Company.
In 1868, he was elected a titular member of the Romanian Academy.
In Bucharest, he founded Revista Carpa?ilor in 1860 and, together with V.
A.
Urechia, published Transac?iuni literare ?i ?tiin?ifice starting in 1872.
His volumes included poetry (Ciasurile de mul?amire a lui Gheorghe Sion, 1844; Din poeziile lui Gheorghe Sion, 1857), plays (Influin?a morala, 1869; La Plevna!, 1878; Dramatice, 1879; Sarutarea, 1888), a travel book (Suvenire de calatoria în Basarabia meridionala, 1857), and memoirs (Suvenire contimpurane, 1888).