Isuf or Jusuf Vrioni (1916–2001) was an Albanian translator, diplomat, and Albanian ambassador to UNESCO.
Vrioni was born in Corfu, Greece, on 16 March 1916 son of Ilias Bey Vrioni.
He spent his youth in Corfu and later in Berat.
With the assignment of his father as Ambassador to France, he moved to Paris in 1925.
On 13 September 1947 he was arrested by the communists and finally in 1950 got a 15-year sentence with forced hard-labor.
He was released in late 1958 and interned in Fier.
In 1960, due to his knowledge of foreign languages he started working as translator in Tirana.
He distinguished himself as a francophone and got respect through the intellectual and artistic circles of that time.
After the fall of communism in Albania, he started working as Director of the Albanian Helsinki Committee for Human Rights.
Following the turmoils of 1997 in Albania, he left for Paris.
In 1998 he was assigned as Representative of Albania at UNESCO.