Enrique Clay Creel Cuilty, sometimes known as Henry Clay Creel (30 August 1854 – 18 August 1931) was a Mexican businessman and politician member of the powerful Creel-Terrazas family of Chihuahua.
He is considered the foremost banker during the Porfirato (1876-1910) and wielded considerable political power, becoming "one of the most hated symbols of the Porfirian regime." He served as governor of Chihuahua on two occasions, ambassador of Mexico to the United States, and served in the cabinet of President Porfirio Díaz as his Minister of Foreign Affairs in the last years of his regime.