Chen Yi-sein (Burmese: ???????; Chinese: ???; Jyutping: can4 jyu4 sing3; 8 January 1924 - 23 March 2005) was a Sino-Burmese scholar who specialized in Burma–China relations from the mid-1950s until his death in March 2005.
He was proficient in Burmese, Chinese and English.
He was one of the first members of the Burma Historical Commission when it was established by U Kaung in January 1955.
Chen served the Commission from 1956 until 1987.Chen was born in Pyapon, Irrawaddy Division, British Burma on 8 January 1924.
A fourth generation Sino-Burmese, Chen's forebears came from Taishan, Guangdong.
He died in Taipei, Taiwan on 23 March 2005.During World War II, Chen served as a translator for the Allied Forces.
Following the war, he served as a history researcher and lecturer at Rangoon University.In December 2012, Thaw Kaung published a book, The Selected Writings of U Yi Sein, a compilation of Chen's writings, including 28 Burmese articles and 7 English articles on Burmese history from the 1st to 20th centuries, with a focus on Sino-Burmese relations and Chinese records of the Pyu people.