Nawab Nabi Bux Khan Bhutto (2 January 1887 – 6 December 1965) was the Pakistani lawyer and political leader who was the member of legislative assembly before Partition of India from unknown date to 14 August 1947.
He was also the brother of Shah Nawaz Bhutto, who later became father of Zulfikar Ali Bhutto.
He is also famous for being father of Mumtaz Bhutto and grandfather of Ameer Bux Bhutto.