Penny Siopis is a South African artist who lives in Cape Town.
She was born in 1953 in Vryburg in the Northern Cape, a little town to which her Greek parents had moved after inheriting a bakery from her maternal grandfather.
Siopis studied Fine Arts at Rhodes University in Makhanda, completing her master's degree in 1976, after which she pursued postgraduate studies at Portsmouth Polytechnic in the United Kingdom.
She taught Fine Arts at the Technikon Natal in Durban from 1980 to 1983.
In 1984 she took up a lectureship at the University of the Witwatersrand in Johannesburg.
During this time she was also visiting research fellow at the University of Leeds (1992–93) and visiting Professor in Fine Arts at Umeå University in Sweden (2000) as part of an interinstitutional exchange.
With an Honorary Doctorate from Rhodes University, Makhanda - Siopis is currently Honorary Professor at Michaelis School of Fine Art, University of Cape Town.