Alessandro Pierini (Italian pronunciation: [ales'sandro pje'ri?ni]; born 22 March 1973) is an Italian retired footballer who played as a defender, and is the assistant manager of Trapani Calcio.
After playing for several clubs in his country, mainly Udinese, he finished his professional career in Spain, where he represented Racing de Santander and Córdoba.
Pierini won one cap for Italy, in 2001.