René Poupardin (27 February 1874 – 23 August 1927) was a French medievalist and paleographer whose most important works were on Burgundy, Provence and the south Italian principalities.
He was an alumnus of the École nationale des chartes and a member of the École française de Rome from 1899 to 1902.
He was studies director at the École pratique des hautes études and later a professor at the École des chartes.
He also worked as a librarian at the Bibliothèque nationale de France.
Born at Le Havre and died at Fontainebleau, most of his life was spent in Paris and Rome.