Edward Tatum, Date of Birth, Place of Birth, Date of Death

    

Edward Tatum

genetics scientist

Date of Birth: 14-Dec-1909

Place of Birth: Boulder, Colorado, United States

Date of Death: 05-Nov-1975

Profession: biochemist, geneticist

Nationality: United States

Zodiac Sign: Sagittarius


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About Edward Tatum

  • Edward Lawrie Tatum (December 14, 1909 – November 5, 1975) was an American geneticist.
  • He shared half of the Nobel Prize in Physiology or Medicine in 1958 with George Beadle for showing that genes control individual steps in metabolism.
  • The other half of that year's award went to Joshua Lederberg. Beadle and Tatum's key experiments involved exposing the bread mold Neurospora crassa to x-rays, causing mutations.
  • In a series of experiments, they showed that these mutations caused changes in specific enzymes involved in metabolic pathways.
  • These experiments, published in 1941, led them to propose a direct link between genes and enzymatic reactions, known as the "one gene, one enzyme" hypothesis. Tatum went on to study genetics in bacteria.
  • An active area of research in his laboratory was to understand the basis of Tryptophan biosynthesis in Escherichia coli.
  • Later, Tatum and his student Joshua Lederberg showed that E.
  • coli could share genetic information through recombination. Tatum was born in Boulder, Colorado.
  • He attended the college at the University of Chicago for two years, and transferred to the University of Wisconsin–Madison, where he received his BA in 1931 and PhD in 1934.
  • Starting in 1937, he worked at Stanford University, where he began his collaboration with Beadle.
  • He then moved to Yale University in 1945 where he mentored Lederberg.
  • He returned to Stanford in 1948 and then joined the faculty of Rockefeller Institute in 1957.
  • A heavy cigarette smoker, he died in New York City of heart failure complicated by chronic emphysema.

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