Adelchi Negri, Date of Birth, Place of Birth, Date of Death

    

Adelchi Negri

Italian microbiologist

Date of Birth: 02-Aug-1876

Place of Birth: Perugia, Umbria, Italy

Date of Death: 19-Feb-1912

Profession: biologist, pathologist

Zodiac Sign: Leo


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About Adelchi Negri

  • Adelchi Negri (2 August 1876 – 19 February 1912) was an Italian pathologist and microbiologist born in Perugia. He studied medicine and surgery at the University of Pavia, where he was a pupil of Camillo Golgi (1843–1926).
  • After graduation in 1900, he became an assistant to Golgi at his pathological institute.
  • In 1909 Negri became a professor of bacteriology, and the first official instructor of bacteriology in Pavia.
  • On 19 February 1912 he died of tuberculosis at age 35. Negri performed extensive research in the fields of histology, hematology, cytology, protozoology and hygiene.
  • In 1903 he discovered the eponymous Negri bodies, defined as cytoplasmatic inclusion bodies located in the Purkinje cells of the cerebellum in cases of rabies in animals and humans.
  • He documented his findings in an article titled Contributo allo studio dell'eziologia della rabia, published in the journal Bollettino della Societa medico-chirurgica.
  • At the time, Negri mistakenly described the pathological agent of rabies as a parasitic protozoa.
  • A few months later, Paul Remlinger (1871–1964) at the Constantinople Imperial Bacteriology Institute correctly demonstrated that the aetiological agent of rabies was not a protozoan, but a filterable virus. Negri went on, however, to demonstrate in 1906 that the smallpox vaccine, then known as "vaccine virus", or "variola vaccinae", was also a filterable virus.
  • During the latter part of his career, he became interested in malaria and was at the forefront in efforts to eradicate it from Lombardy.

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