Henry de Puyjalon (born 15 March 1841 Floirac, Lot, France – died 18 August 1905, l'île à la Chasse, Havre-Saint-Pierre, Mingan Archipelago, Quebec) was a late 19th-century scientist and explorer.
He explored the north coast of the Saint Lawrence River, and was one of the first Canadian ecologists to suggest wildlife and marine conservation areas.
Puyjalon graduated with a Bachelor of Science degree from the University of Toulouse and emigrated to Quebec in 1874.
He became a hunter, trapper, ornithologist, geologist and naturalist, and in 1880, a Quebec government employee with the task to explore for mineral wealth within Labrador.