Mossana Debesai (born 25 November 1993) is an Eritrean professional racing cyclist, who currently rides for UCI Women's Team Servetto–Piumate–Beltrami TSA.She rode in the women's road race at the 2016 UCI Road World Championships, but she did not finish the race.
In 2019, she won the African Road Championships road race and in 2018 and the African Road Championships individual time trial.
She is the younger sister of Mekseb Debesay who won the men's competition in both events.