George Merrick Rice (November 20, 1808 – November 10, 1894) was an American businessman from Worcester, Massachusetts who had a varied career in dry goods and grain retailing and the manufacture of industrial machinery.
He was a pioneer in the steel industry.
He was also a banker, serving as president of the Worcester Safe Deposit and Trust Company.
He was president of the Worcester Common Council for three years and was a member of the Massachusetts State Senate from 1869 to 1870.