She quickly achieved great popularity in the Mexico thanks to her talent, demeanor, and unconventional stature (being very tall for an actresses of the time).
For several years, she was part of the film crew of Juan Orol in his best Gangster films.
Among these are the classic Gangsters Versus Cowboys (1948), considered one of the best Mexican films and considered a Cult film in several film clubs around the world.
Additionally, Rosa Carmina was one of the principal stars of the Rumberas film of the Golden Age of Mexican cinema in the 1940s and 1950s.
Among her principal Rumberas films are Tania, the Beautiful Wild Girl (1947), Wild Love (1949), In the Flesh (1951), Voyager (1952) and Sandra, the Woman of Fire (1954), among others.
In her versatile career, Rosa Carmina has worked in various film genres, as well as theater and television.
In the 1980s and 1990s she appeared in some Mexican telenovelas.
Thanks to her film collaboration with Orol, she was known as The Queen of the Gangsters of Mexican cinema.
She is also known under the name Her Majesty The Rumba.