Christos Karkamanis (Greek: ???st?? ?a??aµ????) (born 22 September 1969 in Thessaloniki) is a former Greek football player.
He played for Aris and Iraklis, as well as for the national side.
He competed at the 1994 FIFA World Cup, where he was the starting goalkeeper in a 0-2 loss against Nigeria.
In July 2007, Karkamanis was signed as the goalkeeping coach for Ethnikos Katerini.