Princess Mabel of Orange-Nassau (Dutch: Prinses Mabel van Oranje-Nassau; formerly Mabel Martine Wisse Smit, born Mabel Martine Los, 11 August 1968) is the widow of Prince Friso and sister-in-law of King Willem-Alexander of the Netherlands.
She is a prominent human rights activist, widely known for her roles in co-founding War Child Netherlands, the European Council on Foreign Relations, Girls Not Brides: The Global Partnership to End Child Marriage, and for having served as the first Chief Executive Officer of The Elders, a grouping founded by Nelson Mandela and chaired by Kofi Annan.
In 2005, the World Economic Forum recognised her as a Young Global Leader.
Van Oranje is an advisor to several non-profits, including the Coalition for the International Criminal Court, the Malala Fund, Crisis Action and the Open Society Foundations.