Irena Degutiene (born 1 June 1949 in Šiauliai, Lithuanian SSR, Soviet Union) is a Lithuanian politician and member of the conservative Homeland Union, currently Deputy Speaker of Seimas.
She was twice the acting Prime Minister of Lithuania, first from 4 May 1999 to 18 May 1999 and then from 27 October 1999 to 3 November 1999.
She has also been the Minister for Social Security and Labour from 1996 to 2000.
In 1978, she graduated from Vilnius University with a degree in medicine.
For almost twenty years, she worked in Vilnius Red Cross Hospital before becoming a secretary in the Ministry of Health in 1994.
In 1996, she was elected to Seimas and re-elected in 2000.
On 15 September 2009 Irena Degutiene became Speaker of Seimas, a position she held until 14 September 2012.
She is the first woman to hold such position in Lithuania's history.