Désirée Artôt (French: [dezi?e a?to]; 11 June 1835 – 3 April 1907) was a Belgian soprano (initially a mezzo-soprano), who was famed in German and Italian opera and sang mainly in Germany.
In 1868 she was engaged, briefly, to Pyotr Ilyich Tchaikovsky, who may have coded her name into works such as his First Piano Concerto and the Romeo and Juliet Fantasy-Overture.
After her 1869 marriage to the Spanish baritone Mariano Padilla y Ramos, she was known as Désirée Artôt de Padilla or Désirée Artôt-Padilla.