Prince Gaetan of the Two Sicilies, Count of Girgenti (Italian: Gaetano Maria Federico, Principe di Borbone delle Due Sicilie, Conte di Girgenti) (12 January 1846, Naples, Two Sicilies – 26 November 1871, Lucerne, Switzerland) was the seventh child of Ferdinand II of the Two Sicilies and his wife Maria Theresa of Austria.
Gaetan was a member of the House of Bourbon-Two Sicilies and consort to Isabella, Princess of Asturias, twice the recognized heir presumptive to the throne of Spain.
Through this union, Gaetan was created an Infante of Spain.