Guillermo "Jorge" Santana (born 13 June 1951) is a Mexican guitarist, brother of musician Carlos Santana.
He was a member of Malo who had a top twenty hit "Suavecito" in 1972.He released two solo albums on Tomato Records, Jorge Santana and It's All About Love, featuring former Malo members.
In the mid-1970s he played with the Fania All-Stars.
His distinctive guitar is a green Fender Stratocaster, acquired in the 1970s.
After a long split, Santana toured with his brother, Carlos.
The album Sacred Fire: Live in South America was recorded in Mexico City on this tour, featuring Jorge Santana, who played a personalized orange Paul Reed Smith guitar.
In 1994 he recorded an album with his brother and Carlos Santana's nephew, Carlos Hernandez, called Santana Brothers.