Mohammad Roem ([mo'hamad 'r?m]; 16 May 1908 in Temanggung 16 May 1908 – 24 September 1983 in Jakarta) was a diplomat and one of Indonesia's leaders in the Indonesian war for independence.
During the Sukarno presidency, he served as Deputy Prime Minister, Foreign Minister, and later Minister of Home Affairs.
He was most notable for his part in the Roem – van Roijen Agreement during the Indonesian revolution.