Previously, she was the 44th Governor of Kansas from 2003 to 2009, the second woman to hold that office.
She is a member of the Democratic Party.
Sebelius was the Democratic respondent to the 2008 State of the Union address and is chair-emerita of the Democratic Governors Association (she was its first female chair).
On April 10, 2014, Sebelius announced her resignation as Secretary of Health and Human Services.