Charles Le Roy (12 February 1726 – 12 December 1779) was an 18th-century French physician and Encyclopédiste.
An advisor to the king, he was professor of medicine at the University of Montpellier, a member of the French Academy of Sciences, the Royal Society, the Société royale de médecine and the Academies of Montpellier, Nîmes and Toulouse.