Dewan Singh Bhakuni (born 1930) is an Indian natural product chemist, stereochemist and a former director general-grade scientist of the Central Drug Research Institute.
He is known for his researches on the biogenesis of alkaloids and is an elected fellow of the Indian Academy of Sciences, the National Academy of Sciences, India and the Indian National Science Academy.
The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1975, for his contributions to chemical sciences.