Adolphe-Marie Gubler (5 April 1821 – 20 April 1879) was a French physician and pharmacologist born in Metz.
Originally a student of botany, he began his medical studies in 1841 at Paris, where he was a pupil of Armand Trousseau (1801–1867).
In 1845 he became an interne des hĂ´pitaux, earning his doctorate in 1849.
In 1868 he was appointed professor of therapy to the medical faculty in Paris, maintaining this position until his death in 1879.
Gubler made a number of contributions in the fields of medicine and pharmacology.
He is credited with being the first physician to differentiate between hemotogenous and hepatogenous icterus.
His name is associated with "Millard-Gubler syndrome", a condition characterized by softening of brain tissue that is caused by blockage of blood vessels of the pons.
The disease is named in conjunction with Auguste Louis Jules Millard (1830–1915), who initially described the disorder in 1855.