Princess and Landgravine Christiane Amalie of Hesse-Homburg, full German name: Christiane Amalie, Landgräfin von Hessen-Homburg (29 June 1774, Bad Homburg vor der Höhe, Landgraviate of Hesse-Homburg, Holy Roman Empire – 3 February 1846, Dessau, Duchy of Anhalt-Dessau) was a member of the House of Hesse-Homburg and a Princess and Landgravine of Hesse-Homburg by birth.
Through her marriage to Frederick, Hereditary Prince of Anhalt-Dessau, Amalie was also a member of the House of Ascania and Hereditary Princess of Anhalt-Dessau.