David Arthur John Tyrrell (1925–2005) was a British virologist.
Born 19 June 1925, he studied medicine at the University of Sheffield, then worked at the Medical Research Council's Common Cold Unit from 1957, becoming its Director from 1982.
He retired from there in 1990 and subsequently carried out research at the Centre for Applied Microbiology and Research at Porton Down, where he also worked on his scientific autobiography, Cold Wars.