Edmé Régnier L'Aîné (15 July 1751 – 10 June 1825) was a French pistol maker and engineer, born in Semur-en-Auxois in 1751 and died in Paris in 1825.
He became the inspector of hand firearms production under the Committee of Public Safety.
Subsequently, he was appointed the first Director of the Musée d'Artillerie in the cloister of the Church of Saint Thomas d'Asquin, Paris.