Harry Isaacs (26 January 1908 in Johannesburg – 13 September 1961) was a South African boxer who competed in the 1928 Summer Olympics in Amsterdam.In his first Olympic bout, he defeated Aage Fahrenholtz of Denmark in a points decision.
In his second Olympic bout, he defeated Canadian boxer Vince Glionna on points.
In his third Olympic bout, he lost to John Daley of the United States on a points decision in the Semi-final round.In his last Olympic bout, he took the bronze medal in the bantamweight class after defeating Frank Traynor of Ireland in a points decision.He died on 13 September 1961 in Johannesburg.